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ACE inhibitors (captopril, enalapril) enhance the activity of antioxidant enzymes (CuZn-SOD, Mn-SOD, and Se-GPx, but not catalase), which suggests these medications possess a protective effect against OxSt [153]
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WangFHeMXiaoJZhangYYuanXFangWet alA randomized, open-label, multicenter, phase 3 study of high-dose vitamin C plus FOLFOX ± Bevacizumab versus FOLFOX ± bevacizumab in unresectable untreated metastatic colorectal cancer (VITALITY Study)
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