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A peptide that modulates VEGFR2 in a cell culture dish, or heals a rat tendon at 10 mcg/kg IP injection, has not been shown to survive oral delivery in a human at 500 mcg and reach musculoskeletal tissue at any meaningful concentration

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Extensive research across various animal models has demonstrated its ability to mitigate optic nerve damage, axon loss, and retinal vascular damage, suggesting its potential to RGCs and their axons (186, 187)