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Furthermore, in a maize cultivar with symptomless SCMV-resistance, a proteomic analysis revealed a down-regulation of two different GSTs in later phases of virus infection, pointing to a role of GSTs in establishing virus resistance at the early stages of pathogenesis (Wu et al., 2013a,b)

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Notably, impaired autophagy has proved to be proved a critical factor involved in a variety of neurodegenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (1)