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PMID: 29687230

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Key takeaways Minoxidil has FDA approval and 30+ years of clinical data showing 40-60% of users experience measurable regrowth GHK-Cu stimulates follicle stem cells and increases hair thickness through copper-dependent growth factor signaling Minoxidil works primarily by extending the anagen (growth) phase and improving blood flow to follicles GHK-Cu has fewer reported side effects than minoxidil but lacks large-scale human hair loss trials Combination use of both compounds may produce better outcomes than either alone, though this hasn't been tested in randomized trials How does minoxidil promote hair growth