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The prevalence of hypothyroidism alone is estimated at 30% of the old population, while hypothyroidism is one of the most common thyroid diseases (4)

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Intensity ratios between the paramagnetic and diamagnetic states were computed for all assigned and non-overlapping 1 H, 15 N, and 1 H, 13 C HSQC cross-peaks, employing a correlation time of the electron-spin interaction vector of 4 ns 52,53

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