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A study from 2007 investigated the effects of Pycnogenol ® on the endothelium-dependent vasodilation by measuring the forearm blood flow in response to acetylcholine, an endothelium-dependent vasodilator (21)

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Firstly, we detected that the expression of CBS and GSH/GSSG ratio in pancreatic tissue were significantly increased, while the level of Hcy was decreased (Figures 1(a)–1(c))