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HKC increased the expression of PPARα and its target genes (such as LPL and aP2), PPARγ and its target genes (such as LPL, CPT-1, ACO, and CYP4A) in the liver and kidneys of DKD rats

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As summarized in Table 1 , the compound exerts potent effects—including inhibition of proliferation, induction of apoptosis, suppression of CSCs, and modulation of the tumor immune microenvironment—across diverse cancer types