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Flavonoids and isoflavones have minimal inhibitory effects on aromatase and 17β-hydroxysteroid dehydrogenases (17β-HSD) in breast cancer cells, and they also hinder the generation of active oestrogens & steroid synthesis within cancer cells (128)

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Pravastatin is selectively taken up by the sodium-independent organic anion transporter protein-1B1 (OATP1B1), which is expressed in hepatocytes [41]