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There are approximately 150,000–160,000 mushroom species on earth, of which only 10% are known to science ( Mushrooms are rich in protein and carbohydrates, with approximately 13–62% of crude protein and 14–75% of carbohydrates in the dry matter for wild-growing mushrooms, whereas they have low content in fat, approximately 0.1–8% ( Diabetes mellitus (DM) is a non-communicable disease characterizing chronic hyperglycemia caused by impaired functions in insulin secretion and/or insulin action ( Interdisciplinary studies focusing on mushrooms have documented much of the knowledge on mushroom polysaccharides and increasingly demonstrate valuably pharmaceutical properties of mushroom polysaccharides extracted from a number of species

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The human growth hormone itself is an ubiquitous hormone with many roles, including the development of children and adolescents by increasing muscle mass