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10.1038/s41467-023-38437-1 26 ConteC.CipponeriE.RodenM

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A direct comparative assessment of the aqueous solubility and reconstitution behavior of TB500 Theymalin Beta-4 versus older legacy formulations indicates that optimized excipient ratios and tailored polar-nonpolar residue distributions prevent unwanted molecular aggregation, allowing for rapid, crystal-clear stock solution preparation without requiring harsh co-solvents or extreme physical agitation