glutathione depletion in alcoholic liver disease Detoxification Pathways: Phases, and Bile Vitamin B12 Deficiency 🔹 Weight:500 g (17.64 oz) Z00BS

glutathione depletion in alcoholic liver disease Detoxification Pathways: Phases, and Bile Vitamin B12 Deficiency 🔹 Weight:500 g (17.64 oz) Z00BS

Vitamin B12 Deficiency 🔹 Causes megaloblastic (macrocytic) anemia 🔹 Needed for DNA synthesis and neurologic function 🔹 Pernicious anemia = classic cause (lack of intrinsic factor) Causes 🔹 Pernicious anemia 🔹 Vegan

Given the vital role of mitochondrial oxidative stress in the pathogenesis of AILI, NAC is used clinically as the only standard antidote to treat AILI, mainly via replenishing GSH to enhance detoxification of NAPQI

Z00BS

Weight:500 g (17.64 oz)

Huang J., Ren R