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The Link Between NSAIDs and Oxidative Stress While NSAIDs are widely used to manage pain and inflammation, emerging research suggests that their long-term use may contribute to oxidative stress, a condition in which free radicals overwhelm the body's antioxidant defenses

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THC exposure has been shown to stimulate the growth of the ER+ MCF-7 cell line (195) and can lead to increased growth and metastasis of tumors with little or no expression of cannabinoid receptors due to suppression of the antitumor immune response (176)