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In vitro glutathione deficiency alters vitamin D metabolism genes and VDR in mouse hepatocytes To rule out the non-specific effect of HFD conditions and other confounding variables in animals, we carried out in vitro experiments to determine the direct impact of glutathione deficiency status on VD metabolism genes in hepatocytes

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In fact, an adult may take doses up to about 2400 mg/day of ALA without severe harmful effects in the short term, although higher doses do not necessarily confer additional benefit

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