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Thymosin beta-4 has been hypothesized as an effective remyelination treatment based on its ability to promote differentiation of oligodendrocyte progenitor cells (OPCs)

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Treatment of Recurrent Disease After Prior Chemotherapy The efficacy of pemetrexed was evaluated in Study JMEI (NCT00004881), a multicenter, randomized (1:1), open-label study conducted in patients with Stage III or IV NSCLC that had recurred or progressed following one prior chemotherapy regimen for advanced disease