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[4] [37] Substrate + NADPH + H + β 5Ξ±-substrate + NADP + Beyond being a catalyst in the rate-limiting step in testosterone reduction, 5Ξ±-reductase isoforms I and II reduce progesterone to 5Ξ±-dihydroprogesterone (5Ξ±-DHP) and deoxycorticosterone to dihydrodeoxycorticosterone (DHDOC)
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For athletes and physique competitors, this effect can: β Accelerate fat loss in a caloric deficit without requiring extreme cardio
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