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Patients with controlled uric acid level and doing well on allopurinol would seem to have no reason to switch to this new agent, in view of allopurinol's lower cost and 40-year history of an overall very good safety record (see "Allopurinol" discussion above)

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In previously published works 2-chloro-1-methylquinolinium tetrafluoroborate (CMQT) or 2-chloro-1-methyllepidinium tetrafluoroborate (CMLT) were applied for the derivatization of Nɛ-Hcy-Lys 10,11,17,21