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After tissue distribution, AITC is conjugated to glutathione in the liver and excreted in the urine as mercapturic acid (AITC-NAC), which accounts for a 50-80% dose of ingestion ITC [27-29]
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This finding suggested that luseogliflozin may be more effective in protecting the kidneys during the transition from AKI to CKD than during the acute phase of AKI
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