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It is also a highly effective option for patients who cannot tolerate the gastrointestinal side effects of gut-directed peptides
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Moreover, a minor proportion of this agent can be metabolized within the liver by the cytochrome P450 enzymes (primarily by CYP2E1) to NAPQI, which is detoxified by conjugation and excreted in the glutathione or NAC forms ( Figure 2 )
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