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Testis were homogenized in 50 mM NaCl, 1 mM EDTA, 1% Triton-X-, and 20-mM TRIS-HCl pH 7.4, by using a IKA Ultra-Turrax homogenizer

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In life-threatening cases, 5,000,000mcg of B12 is given directly to the veins within a 15 minute window