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Studies demonstrate that when TLR5 –/– germ-free mice are infected with adherent-invasive Escherichia coli (AIEC) and subsequently exposed to a specific SPF microbial environment, they develop colitis symptoms (105)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Engevik M.A., Morra C.N., Röth D., Engevik K., Spinler J.K., Devaraj S., Crawford S.E., Estes M.K., Kalkum M., Versalovic J
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