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doi: 10.1039/D1FO03574F

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Elevated ROS levels can regulate autophagy via various pathways, such as by activating the adenosine-monophosphate-activated protein kinase (AMPK) signaling cascade and the unc-51-like kinase 1 complex, oxidizing autophagy-related ATG4, disrupting the Bcl-2/Beclin-1 interaction, and inducing mitophagy, leading to changes in body homeostasis