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Long-term oral supplement use, however, may cause cramping or bloating and could lower zinc levels

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DNA Damage and Mutations: The increase in etheno –dG and –dA DNA adducts, caused by lipid peroxidation in liver tissues from hemochromatosis patients, and the p53 mutational load in liver tissue from individuals with hemochromatosis are both consistent with the hypothesis of generation of oxyradicals as an underlying mechanism of cancer in heavy metal overload diseases