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In contrast, CAR T cells in the day 28 BM of STR had significantly higher expression of PD-1 compared to the pre-infusion product, suggesting that CAR T cells of STR may have acquired an exhausted or over-activated phenotype post-infusion (Fig

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The gut permeability is increased, and the harmful materials (such as endotoxins) are systemically translocated due to the intestinal barrier damage