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Based on these studies, we found that the regulation of ovarian granulosa cells by EVs mainly manifests in two aspects: the proliferation and apoptosis of granulosa cells themselves and the steroidogenesis function of granulosa cells

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S-nitrosylation refers to the covalent modification of protein cysteine residues by NO to form an S-nitrosothiol (SNO) (Lima et al., 2010), and the effect of NO on protein S-nitrosylation is independent of the cGMP/PKG pathway